upset stomachs and hangovers.
But more than even its medicinal qualities, Alka-Seltzer became a triumph in marketing. Hub’s brother Charles invested heavily in sponsoring radio shows, which gave the product a huge bounce. Later, their television commercials proved to be classics. There was Speedy, the tablet’s cartoon spokesperson, who whisked around with a wand making people feel better. An ad depicting a man offering the post-meal lament “I can’t believe I ate that whole thing” was a huge winner in the 1970s and the mantra “plop, plop, fizz, fizz/oh what a relief it is” became ubiquitous in the 1980s. The catchphrase “That’s a spicy meatball” was also part of an Alka-Seltzer campaign.
In large part, the success of Alka-Seltzer made Elkhart a very prosperous locale. At one point, the town reportedly featured forty millionaires—or approximately one in every thousand residents. Alas, Alka-Seltzer and its parent company, which were purchased by Bayer AG in 1977, have since moved the main office. In 2009 Elkhart earned the dubious distinction of having the fastest increasing jobless rate in the United States, jumping from 4.7 percent to 15.3 percent in a single year. Sadly, there are some ills that even a couple of Alka-Seltzer tablets cannot cure.
Artificial Sweeteners: Sloppy scientists
You’d think that rule number one when working with chemical compounds in a lab would be don’t taste anything unless you’re absolutely certain what you’re putting in your mouth. After all, we even tell little kids on the playground to follow that rule. But for those who can’t get through the day without a Diet Pepsi or a Coke Zero, it’s fortunate that apparently many scientists aren’t too worried about following that childhood missive.
Each of the original holy trinity of artificial sweeteners—saccharin, cyclamate, and aspartame (aka NutraSweet)—was discovered by researchers who just didn’t think to wash their hands. As for the most recent, and today’s most popular, artificial sweetener, sucralose (known on the street as Splenda), it has its own different but equally accidental origin story.
Saccharin was the original sugar substitute. In 1879 one of the century’s most revered chemists, Ira Remsen, was doing research on coal tar derivatives. (If you wonder why saccharin has that awful aftertaste, coal derivatives might give you some sense.) During research, an associate, Constantin Fahlberg, accidentally spilled some of a substance he was preparing on his hands. Overcome by intellectual curiosity—rather than common sense—he took a lick and found it to be incredibly flavorful. It turned out that the mixture was 300 times as sweet as basic sugar. He named it saccharin after the Latin word for sugarcane, saccharum .
While saccharin went on the market as an alternative to sugar, its bitter aftertaste did somewhat limit its value. What was needed was another sweetener to mix with it that could lessen the bite. Cyclamate, which was discovered in 1937, wasn’t as sweet as saccharin, but proved to be its potential partner (though some studies have indicated the combo can cause cancer). Yet again, its discovery came from another messy scientist.
Michael Sveda was a student at the University of Illinois working on some sulfamates that were expected to have promising pharmacological properties. He got his hands dirty—so to speak—mixing these compounds and didn’t think anything of it when he went for a cigarette break. After taking a long drag from his smoke, he noticed something very odd: Chemicals on his hands from the experiments had soaked into the cigarette creating a sweet taste.
Proving that scientists don’t always learn from the past, James M. Schlatter had his own unclean story when it came to finding the combination that led to Equal and NutraSweet. In December 1965, after getting some aspartame powder on his hands, he licked a finger in order to help pick up a piece
But more than even its medicinal qualities, Alka-Seltzer became a triumph in marketing. Hub’s brother Charles invested heavily in sponsoring radio shows, which gave the product a huge bounce. Later, their television commercials proved to be classics. There was Speedy, the tablet’s cartoon spokesperson, who whisked around with a wand making people feel better. An ad depicting a man offering the post-meal lament “I can’t believe I ate that whole thing” was a huge winner in the 1970s and the mantra “plop, plop, fizz, fizz/oh what a relief it is” became ubiquitous in the 1980s. The catchphrase “That’s a spicy meatball” was also part of an Alka-Seltzer campaign.
In large part, the success of Alka-Seltzer made Elkhart a very prosperous locale. At one point, the town reportedly featured forty millionaires—or approximately one in every thousand residents. Alas, Alka-Seltzer and its parent company, which were purchased by Bayer AG in 1977, have since moved the main office. In 2009 Elkhart earned the dubious distinction of having the fastest increasing jobless rate in the United States, jumping from 4.7 percent to 15.3 percent in a single year. Sadly, there are some ills that even a couple of Alka-Seltzer tablets cannot cure.
Artificial Sweeteners: Sloppy scientists
You’d think that rule number one when working with chemical compounds in a lab would be don’t taste anything unless you’re absolutely certain what you’re putting in your mouth. After all, we even tell little kids on the playground to follow that rule. But for those who can’t get through the day without a Diet Pepsi or a Coke Zero, it’s fortunate that apparently many scientists aren’t too worried about following that childhood missive.
Each of the original holy trinity of artificial sweeteners—saccharin, cyclamate, and aspartame (aka NutraSweet)—was discovered by researchers who just didn’t think to wash their hands. As for the most recent, and today’s most popular, artificial sweetener, sucralose (known on the street as Splenda), it has its own different but equally accidental origin story.
Saccharin was the original sugar substitute. In 1879 one of the century’s most revered chemists, Ira Remsen, was doing research on coal tar derivatives. (If you wonder why saccharin has that awful aftertaste, coal derivatives might give you some sense.) During research, an associate, Constantin Fahlberg, accidentally spilled some of a substance he was preparing on his hands. Overcome by intellectual curiosity—rather than common sense—he took a lick and found it to be incredibly flavorful. It turned out that the mixture was 300 times as sweet as basic sugar. He named it saccharin after the Latin word for sugarcane, saccharum .
While saccharin went on the market as an alternative to sugar, its bitter aftertaste did somewhat limit its value. What was needed was another sweetener to mix with it that could lessen the bite. Cyclamate, which was discovered in 1937, wasn’t as sweet as saccharin, but proved to be its potential partner (though some studies have indicated the combo can cause cancer). Yet again, its discovery came from another messy scientist.
Michael Sveda was a student at the University of Illinois working on some sulfamates that were expected to have promising pharmacological properties. He got his hands dirty—so to speak—mixing these compounds and didn’t think anything of it when he went for a cigarette break. After taking a long drag from his smoke, he noticed something very odd: Chemicals on his hands from the experiments had soaked into the cigarette creating a sweet taste.
Proving that scientists don’t always learn from the past, James M. Schlatter had his own unclean story when it came to finding the combination that led to Equal and NutraSweet. In December 1965, after getting some aspartame powder on his hands, he licked a finger in order to help pick up a piece
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