uh, with her pantyhose.â
âPantyhose?â
I giggled. âJust a run.â
âJust a run? Hey, tell her Iâll buy her a new pair. She sounds sexy.â
âWhat?â I said in surprise.
âI love her voice. Deep and husky.â
âSheâs not your type, Bob.â
âHow do you know?â
âTrust me.â
âDescribe her.â
I chuckled. âWell, sheâs tall.â
âBlond?â
âActually, yes.â
âSounds better every minute. Built?â
I chuckled. âYou mean chest size?â
âWell, sure.â
âBig.â
âHow big is âbigâ?â
âAt least forty-two inches.â
âPraise the Lord.â
I could barely keep from laughing. âTell you what, Bob, Iâll fix you two up next time youâre out here.â
âYouâre a true pal, Rachel.â
âDonât thank me, yet. Meanwhile, back to business. You were telling me about some work you did with a pharmaceutical company.â
âOh, yeah. The due diligence stuff with McNeil Pharmaceutical. Do you know anything about the economics of the drug industry?â
âNot really,â I admitted, taking notes.
âYou canât sell a new drug in the United States without first going through an incredibly rigorous system of approvals supervised by the Food and Drug Administration.â
âI knew that much.â
âWell, thatâs where the economics come in. On average, it takes eight to ten years and fifty to eighty million dollars to bring a new drug from the original concept through the FDA process to the market.â
âWow.â
âExactly. Moreover, the odds against a new drug surviving all the way are steep. The guys at McNeil had statistics showing that only one out of every four thousand drugs that undergo preclinical testing ever makes it to the market. Even if you get past the preclinical phase to the human testing stage, which is pretty far down the process, your odds of making it to the market are still only one of five. You know what that means?â
âIâm not sure,â I mumbled as I finished scribbling: 1 out of 5â human testing to market .
âIt means that youâve got to do some serious due diligence before you have a sense of what a pharmaceutical company is really worth. For example, you need to find out the status of the IND applications.â
âThe what?â
âIND. It stands for Investigational New Drug.â
âLet me write that down.â
As I was scribbling, Jacki came in. âI found it,â she whispered, holding up a bottle of clear nail polish.
âBob, can I have one more pantyhose timeout?â
âNo problem. Tell your secretary Iâm falling in love long distance.â
I rested the receiver against my neck. âHereâs how you do it,â I said to her, reaching for the bottle of nail polish. I unscrewed the top. âCome closer.â She did. I slid out the brush and leaned toward her leg. âJust like this. Put a little dab at the end of the run. Let it dry. Itâll keep the run from getting any longer.â I leaned back with a smile, screwed on the top and held it out to her. âThere. All done.â
Jacki gave me a look of gratitude as she took the bottle of nail polish. âThanks so much, Rachel.â She glanced down at the stocking. âThatâs wonderful.â
I lifted the receiver to my ear. âIâm back,â I said to Bob.
âWow, thatâs better than phone sex.â
âBack to business, stud.â I glanced at my notes. âIND. You said it stands for Investigational New Drug. Whatâs that?â
âOkay. When a drug company has finished all of its preliminary testing on animals and wants to move to the next stage of the approval process, which is testing the drug on humans, it files an IND application with the FDA. Among other
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